Malignancies in Deceased Organ Donors: The Spanish Experience.

BACKGROUND: To better define the risk of malignancy transmission through organ transplantation, we review the Spanish experience on donor malignancies. METHODS: We analyzed the outcomes of recipients of organs obtained from deceased donors diagnosed with a malignancy during 2013-2018. The risk of malignancy transmission was classified as proposed by the Council of Europe. RESULTS: Of 10 076 utilized deceased donors, 349 (3.5%) were diagnosed with a malignancy. Of those, 275 had a past (n = 168) or current (n = 107) history of malignancy known before the transplantation of organs into 651 recipients. Ten malignancies met high-risk criteria. No donor-transmitted cancer (DTC) was reported after a median follow-up of 24 (interquartile range [IQR]: 19-25) mo. The other 74 donors were diagnosed with a malignancy after transplantation. Within this group, 64 donors (22 with malignancies of high or unacceptable risk) whose organs were transplanted into 126 recipients did not result in a DTC after a median follow-up of 26 (IQR: 22-37) mo, though a prophylactic transplantectomy was performed in 5 patients. The remaining 10 donors transmitted an occult malignancy to 16 of 25 recipients, consisting of lung cancer (n = 9), duodenal adenocarcinoma (n = 2), renal cell carcinoma (n = 2), extrahepatic cholangiocarcinoma (n = 1), prostate cancer (n = 1), and undifferentiated cancer (n = 1). After a median follow-up of 14 (IQR: 11-24) mo following diagnosis, the evolution was fatal in 9 recipients. In total, of 802 recipients at risk, 16 (2%) developed a DTC, which corresponds to 6 cases per 10 000 organ transplants. CONCLUSIONS: Current standards may overestimate the risk of malignancy transmission. DTC is an infrequent but difficult to eliminate complication.

The urgent need to achieve an optimal strategic stock of human allogeneic skin graft materials in case of a mass disaster in Poland.

A burn is a sudden injury which immediate or long-term consequences may be life-threatening for the patient. A mass disaster event may involve large numbers of severely burned patients. Patients of this type typically have a limited area of healthy, unburned skin from which an autologous split thickness skin graft could be collected. In a clinical situation of this type, it is necessary to use a particular skin substitute. Non-viable allogeneic human skin graft materials might be considered as the most suitable skin substitutes in the treatment of such patients. At present, Poland does not have a sufficient supply of human allogeneic skin graft materials to meet the needs arising from a sudden and unforeseen mass disaster. This study involved an analysis of selected mass disasters. From this an estimate was made from a verified casualty profile of the necessary minimum stock of human allogeneic skin graft materials. An insufficient amount of skin results from an inadequate number of skin donors, which in turn results from the current tissue donation system. Therefore, a proposal has been made for the organizational, legal and systemic changes required to improve the situation in Polish transplantology, with particular emphasis on skin donation. In order to achieve a strategic stock of human skin grafts, a tissue collecting transplantation team should be organized. The rights and obligations of the non-physician transplant team member should be extended. Proposals have been made for awareness campaigns (adverts, posters etc.) and educational schemes (educational video, lectures during transplant coordinator training, etc.). Finally, a proposal has been made for possible methods to deal with the logistic management of the allogeneic skin stock. The required, essential stock of human allogeneic skin in the event of a mass disaster has been estimated at 600,000 cm2.

Learning from incidents in medically assisted reproduction: the Notify Library as a learning tool.

Biovigilance is the systematic monitoring of serious adverse reactions and events (SARE) that ensures the quality and safety of tissues and cells for human application in medically assisted reproduction (MAR). The Notify Library is an open access database launched by the World Health Organization and supported by the Italian National Transplant Centre (CNT) that has collected information on documented adverse occurrences in transplantation, transfusion and MAR. It is not a SARE register, but rather a collection of SARE types identified primarily by review of published articles and case reports from national or regional vigilance programmes. The Notify Library includes many well-documented records of adverse occurrences in MAR treatment, representing a useful tool for MAR operators in the evaluation of the risks associated with the clinical application of reproductive tissues and cells. It is updated with new records when a new type of incident is reported for the first time. All incident types described might have teaching value during the risk management carried out by a MAR centre. Sharing lessons learned from these incidents represents an important didactic opportunity that can help MAR centres to improve their processes and to achieve higher standards of quality and safety.

Leadership, management, quality, and innovation in organ donation: 2019 Kunming recommendations for One Belt & One Road countries.

The findings and recommendations of the 2019 consensus conference in organ donation, held in Kunming, China, are here reported. The main objective of the conference was to gather relevant information from experts involved in the field. The data and opinions provided allowed to propose a series of recommendations for "One Belt & One Road Countries" on how to achieve self-sufficiency in organ donation. Leadership in organ donation should be results-oriented and goal-driven based on the principles of excellence, empowerment, and engagement, providing the means, resources, and strategies necessary to reach the goal in earnest. Management includes good governance and transparency of a national registry of patients in the waiting list, donors, transplants, transplant teams, quality, and safety programs with continuous educational training of health care professionals. Mandatory monitoring, auditing and evaluation of quality must be incorporated into donation practices as relevant points in innovation, as well as the adoption of already established and novel processes and technologies. Achievement of self-sufficiency in organ donation is a crucial step to fight against transplant tourism and to prevent organ trafficking. Based on recommendations arising from the conference, each country could review and develop individualized action plans adjusted to its own circumstances and reality.

Leadership, management, quality, and innovation in organ donation: 2019 Kunming recommendations for One Belt & One Road countries

ABSTRACT The findings and recommendations of the 2019 consensus conference in organ donation, held in Kunming, China, are here reported. The main objective of the conference was to gather relevant information from experts involved in the field. The data and opinions provided allowed to propose a series of recommendations for "One Belt & One Road Countries" on how to achieve self-sufficiency in organ donation. Leadership in organ donation should be results-oriented and goal-driven based on the principles of excellence, empowerment, and engagement, providing the means, resources, and strategies necessary to reach the goal in earnest. Management includes good governance and transparency of a national registry of patients in the waiting list, donors, transplants, transplant teams, quality, and safety programs with continuous educational training of health care professionals. Mandatory monitoring, auditing and evaluation of quality must be incorporated into donation practices as relevant points in innovation, as well as the adoption of already established and novel processes and technologies. Achievement of self-sufficiency in organ donation is a crucial step to fight against transplant tourism and to prevent organ trafficking. Based on recommendations arising from the conference, each country could review and develop individualized action plans adjusted to its own circumstances and reality.

Vigilance for Medical Products of Human Origin-Progress on the Notify Library's Global Effort to Share Information and Learning.

BACKGROUND: World Health Assembly Resolution 63.22 mandated World Health Organization to facilitate Member State access to appropriate information on medical products of human origin (MPHO), including collecting data on serious adverse events and reactions. To meet this challenge, the Italian National Transplant Center, with a mandate from World Health Organization, has built and maintained an open-access searchable database of instructive records on disease transmission and other MPHO adverse occurrences. METHODS: One record in the Notify Library describes a specific type of adverse occurrence in 1 type of MPHO and might be linked with 1 or multiple different references. The record inclusion criteria are that it has been reliably documented in a published article or official vigilance reporting system and that it has instructive value for the fields of transfusion, transplantation, or assisted reproduction. The selection and review of references for publication is performed by international experts who collaborate in 5 topic-specific editorial groups: infection transmission, malignancy transmission, living-donor reactions, process-related incidents, and clinical complications. New relevant references are identified through systematic searches and proactive communication by the experts. RESULTS: The Library contains 1733 records, quoting 2632 references. Of the records, 41.8% are related to organs, 20.8% to blood and blood components, 16.5% to hematopoietic progenitor cells, 15.2% to tissues, 4.2% to reproductive tissues and cells, and 1.5% to other MPHO. CONCLUSIONS: Notify Library is the first open-access, searchable database of systematically identified reports of disease transmission and other adverse occurrences arising from the donation and clinical application of MPHO.

Results of Kidney Transplants From Deceased Donors Discarded From Transplantation by a Regional Transplant Center but Accepted and Transplanted by Another Center.

BACKGROUND: Kidney allocation policy in Poland is strictly patient oriented. Kidneys are transplanted by the same center that made procurement. Sometimes kidneys are transferred for transplantation to another center due to medical or logistic reasons or according to allocation rules. AIM: The aim of the study was to compare early graft and recipient survival rates in cases of kidneys exported for transplantation to another center and in cases of kidneys transplanted typically. METHODS: Data came from national transplant registry. Kidney transplants from the years 2008 to 2017 were divided into several groups. One-year graft and patient survival rates were calculated for each group, and statistical differences were cross-calculated between groups. RESULTS: Groups were compared by using the χ2 test. Statistical analysis showed significantly lower graft and recipient survival rates: in the group of kidney transplantations performed in another transplant centers vs group of kidneys not transferred, where kidney transplantations were performed in a regional transplant center (P = .005 and = .02); and in the group of kidneys transferred due to logistic reason and allocation rules vs group of kidneys not transferred, where kidney transplantations were performed in regional transplant center (P = .01 and = .04). CONCLUSION: Early results of kidneys procured and transplanted by the same regional transplant center are significantly better than kidneys that have been transferred for transplantation to another center, but this result concerns only the subgroup of kidneys shifted due to logistic or allocation reasons. Early results of kidneys discarded by a regional team due to medical reasons and transplanted by another team are not different from results of transplantations performed by the same center that made the procurement.

Factors Associated with Meat Consumption in Students of Spanish Universities: UniHcos Project.

The level of meat consumption is one of the main deviations from the Mediterranean diet pattern in Spanish university students. The objective of this cross-sectional descriptive study is to analyze the association between sociodemographic factors and the consumption of fresh and processed meat in Spanish university students. This study is part of a cohort of 11 Spanish universities with 9862 university students (UniHcos Project). A descriptive analysis and a chi2 test were carried out to assess differences between personal and sociodemographic variables and meat consumption, and binary logistic regression analysis to assess factors associated with consumption; 19.9% and 73.5% met the recommendations for meat-fresh and meat-processed consumption, respectively. Only 3.8% of students meet the recommendations for both fresh and processed meat. Statistically significant differences were found between sex, BMI, employment, housing, and coexistence regarding compliance with recommendations. Female employed students living in rental accommodations with a partner are more likely to meet the recommendations for fresh meats while male, normal weight, employed students living in rental accommodations with a partner are more likely to meet the recommendations for processed meats. There is a lack of compliance with the recommendations for consumption of fresh meat in Spanish university students, differences in compliance among students of differing regions and an association with sex, employment, housing, and coexistence regarding compliance.

Platelet-Rich Plasma Injections for Advanced Knee Osteoarthritis: A Prospective, Randomized, Double-Blinded Clinical Trial.

BACKGROUND: Intra-articular injections of platelet-rich plasma (PRP) to treat symptoms of knee osteoarthritis (OA) have been successfully used in young patients and in the early stages of disease. No previous studies have analyzed outcomes of PRP injections during the late stages. HYPOTHESIS: PRP reduces pain and leads to a more effective and lasting functional recovery than corticosteroid with local anesthetic. STUDY DESIGN: Randomized controlled trial; Level of evidence, 2. METHODS: A total of 75 patients with symptomatic knee OA (Kellgren-Lawrence grade 3 to 4) were enrolled in this study between August 2013 and July 2014. Patients were randomized to treatment either with a single leukocyte-reduced PRP or corticosteroid intra-articular injection. The primary variable was visual analog scale assessment at 1 month. Secondary outcomes were the Knee injury and Osteoarthritis Outcome Score (KOOS) and Short Form-36 (SF-36) at 1, 3, and 6 months after treatment. Patient satisfaction at final follow-up was assessed. Both groups were homogeneous and comparable in baseline characteristics. RESULTS: All variables improved in both groups. Statistical differences between groups were not found for the majority of the outcome variables, although the magnitude of improvements tended to be greater in the PRP group. Quality-of-life differences between values at 3 and 6 months versus baseline increased significantly more in the study group (P = .05 and .03, respectively), and so did general health perception differences at 6 months (P = .018). CONCLUSION: A single PRP intra-articular injection is effective for relieving pain and improving activities of daily living and quality of life in late-stage knee OA. For patients with late-stage knee OA who are 67 years or older, 1 intra-articular injection of PRP has similar results to 1 shot of corticosteroid.

[Not Available]. / Estudio de factores de riesgo de enfermedad cardiovascular en trabajadores universitarios españoles.

UNLABELLED: Introducción y objetivos: las enfermedades cardiovasculares (ECV) son la principal causa de muerte mundial, por ello el objetivo de este estudio es analizar los factores de riesgo de ECV en los trabajadores de la Universidad de Alicante.Material y métodos: estudio transversal descriptivo. Muestra aleatoria (n = 124), 46,6% mujeres y 53,4% hombres, de edades entre 25-68 años. Recogida de datos mediante cuestionario online autocumplimentado. VARIABLES: sociodemográficas, peso y talla autorreferidos, consumo de tabaco, actividad física, consumo diario de aceite de oliva, hortalizas-verduras, mantequilla-margarina-nata y consumo semanal de repostería comercial y frutos secos. Se realizó un análisis descriptivo con el paquete estadístico SPSS 19.0.Resultados: el 12% de mujeres y el 10,5% de los hombres mayores de 44 años presentan obesidad; además, el 32% de mujeres y el 23,7% de los hombres no realizan actividad física. Consume aceite de oliva a diario el total de la muestra a estudio.Conclusión: los hábitos alimentarios de los estudiados se asemejan a los patrones dietéticos mediterráneos considerados saludables. Destacar el cumplimiento de las recomendaciones de consumo de aceite de oliva y la realización de actividad física habitual como protectores de las ECV. El entorno laboral de la población estudiada favorece unos hábitos saludables.

Estudio de factores de riesgo de enfermedad cardiovascular en trabajadores universitarios españoles / Study of risk factors for cardiovascular disease in Spanish university workers

Introducción y objetivos: las enfermedades cardiovasculares (ECV) son la principal causa de muerte mundial, por ello el objetivo de este estudio es analizar los factores de riesgo de ECV en los trabajadores de la Universidad de Alicante. Material y métodos: estudio transversal descriptivo. Muestra aleatoria (n = 124), 46,6% mujeres y 53,4% hombres, de edades entre 25-68 años. Recogida de datos mediante cuestionario online autocumplimentado. Variables: sociodemográficas, peso y talla autorreferidos, consumo de tabaco, actividad física, consumo diario de aceite de oliva, hortalizas-verduras, mantequilla-margarina-nata y consumo semanal de repostería comercial y frutos secos. Se realizó un análisis descriptivo con el paquete estadístico SPSS 19.0. Resultados: el 12% de mujeres y el 10,5% de los hombres mayores de 44 años presentan obesidad; además, el 32% de mujeres y el 23,7% de los hombres no realizan actividad física. Consume aceite de oliva a diario el total de la muestra a estudio. Conclusión: los hábitos alimentarios de los estudiados se asemejan a los patrones dietéticos mediterráneos considerados saludables. Destacar el cumplimiento de las recomendaciones de consumo de aceite de oliva y la realización de actividad física habitual como protectores de las ECV. El entorno laboral de la población estudiada favorece unos hábitos saludables (AU)

Background and objectives: Cardiovascular diseases (CVD) are the leading cause of death worldwide, so the aim of this study is to analyze the risk factors of cardiovascular disease in workers at the University of Alicante (Alicante, Spain). Material and methods: Descriptive transversal study. Random sample (n = 124), 46.6% women and 53.4% men, aged between 25-68 years. On-line data collection by self-completed questionnaire. Variables: socio-demographic, self-referred weight and height, smoking habit, physical activity, daily consumption of olive oil, fruit-vegetables, butter-margarine-cream and weekly consumption of industrial baking and nuts. A descriptive analysis using SPSS 19.0 statistical package was performed. Results: 12% of women and 10.5% of men over 44 years were classified as obese. Otherwise, 32% and 23.7% of women and men respectively, do not practice any exercise routinely. Olive oil is consumed daily by all the sample studied. Conclusion: The studied eating habits are similar to those considered healthy Mediterranean dietary patterns. Daily olive oil consumption together with regular physical activity has an important role as protectors of CVD. The work environment studied has a positive influence in healthy habits (AU)

Navegación y cáncer de mama: una intervención basada en las pacientes / Navigation and breast cancer: a patient-based intervention

ResumenEn Costa Rica el cáncer representa un problema de salud pública debido a la alta incidencia y mortalidad. Las tasas de incidencia de cáncer han aumentado entre 1995 al 2010 en un 48%. Actualmente, el cáncer representa la segunda causa de muerte en el país, sólo superada por las enfermedades del sistema circulatorio. En las mujeres, el cáncer de mama es el segundo en frecuencia y en el 2010 se diagnosticaron 18 casos nuevos casos por semana (tasa 12.04 por cada 100.000 mujeres) para un total de 939. Además, anualmente fallecen 288 mujeres, lo que corresponde a un 15.45% del total de los casos (1).Este artículo presenta la experiencia del proyecto Mujeres que Salvan Vidas como una iniciativa de enlace universidad- sociedad civil-sistema de salud que surge a partir de la realidad del cáncer de mama en el país. Este proyecto de promoción de la salud plantea mejorar la atención a las mujeres con diagnóstico de cáncer de mama a través de la reorganización de los servicios de salud y de la participación comunitaria. En este documento se presenta el Modelo costarricense de navegación de pacientes, así como los resultados iniciales de la implementación del mismo.En el caso costarricense el objetivo de la navegación es orientar a las mujeres con patología mamaria en el transitar por el sistema de salud costarricense. La navegación, se presenta a las pacientes como un servicio de los hospitales participantes.

[VARIABLES USED IN QUESTIONNAIRES ABOUT ERGONUTRITIONALS SUPPLEMENTS INTAKE]. / VARIABLES UTILIZADAS EN CUESTIONARIOS DE CONSUMO DE SUPLEMENTOS ERGONUTRICIONALES.

INTRODUCTION: nutritional supplements intake is increasing during the recent years both in Spain and in the rest of the world. Questionnaires that estimate the intake and supplement use have methodological limitations. The purpose of this study is to describe used indicators in questionnaires that estimate nutritional supplements intake among athletes so facilitate understanding of these limitations. METHODOLOGY: a literature review of variables used within questionnaires to estimate consumption of nutritional supplements among athletes. We conducted a structured research in PubMed database and through snow ball strategy. Search equation: "Questionnaire" AND "Supplementation" AND "Athletes". INCLUSION CRITERIA: published in any country in English or Spanish, containing questionnaire or indicators can be deducted from the items, to estimate the intake and use of nutritional supplements and should be targeted to athletes training in order to compete at any level. We performed a descriptive analysis. RESULTS: 21 above the 122 identified studies met the inclusion criteria. Sociodemographic factors, sport and training frequency, athlete population, reasons/motives for use and consumption, sources of information and list of supplements and frequency are the found indicators for estimating intake of supplements. DISCUSSION: there are great heterogeneity in terms of the proposed indicators by the authors at the questionnaires and intake estimation using nutritional supplements, standardization of the methodology for the development questionnaires to be necessary and proposing the classification of the Australian Institute of Sport as a reference.

Introducción: el consumo de suplementos ergonutricionales está aumentando en los últimos años tanto en España como en el resto del mundo. Los cuestionarios que estiman la ingesta y uso de suplementos presentan limitaciones metodológicas. El objetivo de este estudio es describir las variables utilizadas en los cuestionarios de estimación de consumo de suplementos ergonutricionales para población deportista, descritas en el apartado de metodología de los artículos científicos. Metodología: revisión bibliográfica de variables utilizadas para estimar el uso y consumo de suplementos ergonutricionales. Búsqueda estructurada en la base de datos PubMed y mediante la estrategia bola de nieve. Ecuación de búsqueda: "Questionnaire" AND "Supplementation" AND "Athletes". Criterios de inclusión: artículos publicados en cualquier país en idioma inglés o en español, que contengan cuestionario en el anexo o las variables que se describen en el apartado de metodología que puedan inferirse a partir de los artículos, que estimen la ingesta y uso de suplementos ergonutricionales y vayan dirigidos a deportistas que entrenan a nivel competitivo (amateurs, élite, etc.). Se realizó un análisis de contenido y un análisis descriptivo. Resultados: de los 122 estudios identificados, 21 cumplieron los criterios de inclusión. Las variables descritas fueron factores sociodemográficos y relacionados con el deporte que se practica, así como la frecuencia de entrenamiento, población deportista a la que iba dirigida, razones/ motivos de uso y consumo, fuentes de información, lista de suplementos y frecuencia de uso y consumo. Discusión: existe gran heterogeneidad en cuanto a las variables propuestas por los autores en los cuestionarios de estimación de ingesta y uso de suplementos ergonutricionales. Es necesaria la estandarización de metodologías en el diseño de cuestionarios, así como definir una clasificación de referencia como la propuesta por el Instituto Australiano del Deporte.

[BODY COMPOSITION AND SOMATOTYPE IN UNIVERSITY TRIATHLETES]. / COMPOSICIÓN CORPORAL Y SOMATOTIPO EN TRIATLETAS UNIVERSITARIOS.

INTRODUCTION: the triathlon is an endurance sport and individual that consists of three different disciplines: swimming, cycling and running. The aim of the study was to describe and analyze the anthropometric characteristics, body composition and somatotype in male college triathletes. METHODOLOGY: observational and descriptive study of anthropometric characteristics, body composition and somatotype of 39 male college athletes from 24 ± 4,5 years, participants in the championship of Spain university triathlon sprint mode (Alicante 2010), from different universities Spanish. According to anthropometric measurement techniques adopted by the International Society for the Advancement of Kinanthropometry (ISAK) and the Spanish Group Cineantropometría (GREC) by an accredited assessor ISAK Level II. RESULTS: we find athletes of stunting, where you destacanvalores below normal in the subscapularis, supraspinatus, triceps and biceps skinfold, percentage of muscle mass (45.27 ± 3.29%) and fat mass (10.22 ± 2.92%) and bone (16.65 ± 1.34%) and where mesomorphy somatotipo predominates. DISCUSSION: the triathletes and runners have lower size that cyclists and swimmers. Triathletes and cyclists show a similar weight, less than swimmers line, and more than 10km runners. Iliac crest skinfold, abdominal and thigh front cyclists are less than triathletes. The percentage of fat mass of runners triathletes and swimmers are similar, however the muscle mass of athletes usually less than cyclists but similar to other forms. Somatotype resembles triathlete cyclist (mesomorph). The corridor is ectomorph and mesomorph-swimmer can range from a ectomorph mesomorph.

Introducción: el triatlón es un deporte de resistencia e individual que está formado por tres disciplinas diferentes: natación, ciclismo y carrera a pie. El objetivo del estudio es describir las características antropométricas en triatletas varones universitarios, además de analizar y describir la composición corporal y el somatotipo de dichos triatletas. Metodología: estudio observacional y descriptivo de las características antropométricas, la composición corporal y el somatotipo de 39 triatletas varones universitarios entre 24 ± 4,5 años, participantes en el campeonato de España universitario de triatlón, modalidad sprint (Alicante 2010), procedentes de diferentes universidades españolas. Según la técnicas de medición antropométrica adoptadas por la International Society for the Advancement of Kinanthropometry (ISAK) y el Grupo Español de Cineantropometría (GREC) por un evaluador acreditado ISAK de nivel II. Resultados: nos encontramos con deportistas de talla baja, en los que destacan valores inferiores a lo normal en los pliegues cutáneos subescapular, supraespinal, tricipital y bicipital, un porcentaje de masa muscular (45,27 ± 3,29%), de masa grasa (10,22 ± 2,92%) y de masa ósea (16,65 ± 1,34%) y un somatotipo en el que predomina la mesomorfia. Discusión: los triatletas y corredores presentan más baja talla que los ciclistas y nadadores. Los triatletas y ciclistas muestran un peso similar, siendo menor que el de los nadadores de fondo y mayor que el de los corredores de 10 km. Los pliegues cutáneos cresta ilíaca, abdominal y muslo frontal de los ciclistas son inferiores al de los triatletas. El porcentaje de masa grasa de triatletas corredores y nadadores son similares; sin embargo, el de la masa muscular de los triatletas suele ser inferior al de los ciclistas pero similar a las demás modalidades. El somatotipo del triatleta se asemeja al del ciclista (mesomorfo). El del corredor es mesomorfo-ectomorfo y el del nadador puede oscilar de mesomorfo a ectomorfo.

Variables utilizadas en cuestionarios de consumo de suplementos ergonutricionales / Variables used in questionnaires about ergonutritionals supplements intake

Introducción: el consumo de suplementos ergonutricionales está aumentando en los últimos años tanto en España como en el resto del mundo. Los cuestionarios que estiman la ingesta y uso de suplementos presentan limitaciones metodológicas. El objetivo de este estudio es describir las variables utilizadas en los cuestionarios de estimación de consumo de suplementos ergonutricionales para población deportista, descritas en el apartado de metodología de los artículos científicos. Metodología: revisión bibliográfica de variables utilizadas para estimar el uso y consumo de suplementos ergonutricionales. Búsqueda estructurada en la base de datos PubMed y mediante la estrategia bola de nieve. Ecuación de búsqueda: 'Questionnaire' AND 'Supplementation' AND 'Athletes'. Criterios de inclusión: artículos publicados en cualquier país en idioma inglés o en español, que contengan cuestionario en el anexo o las variables que se describen en el apartado de metodología que puedan inferirse a partir de los artículos, que estimen la ingesta y uso de suplementos ergonutricionales y vayan dirigidos a deportistas que entrenan a nivel competitivo (amateurs, élite, etc.). Se realizó un análisis de contenido y un análisis descriptivo. Resultados: de los 122 estudios identificados, 21 cumplieron los criterios de inclusión. Las variables descritas fueron factores sociodemográficos y relacionados con el deporte que se practica, así como la frecuencia de entrenamiento, población deportista a la que iba dirigida, razones/motivos de uso y consumo, fuentes de información, lista de suplementos y frecuencia de uso y consumo. Discusión: existe gran heterogeneidad en cuanto a las variables propuestas por los autores en los cuestionarios de estimación de ingesta y uso de suplementos ergonutricionales. Es necesaria la estandarización de metodologías en el diseño de cuestionarios, así como definir una clasificación de referencia como la propuesta por el Instituto Australiano del Deporte (AU)

Introduction: nutritional supplements intake is increasing during the recent years both in Spain and in the rest of the world. Questionnaires that estimate the intake and supplement use have methodological limitations. The purpose of this study is to describe used indicators in questionnaires that estimate nutritional supplements intake among athletes so facilitate understanding of these limitations. Methodology: a literature review of variables used within questionnaires to estimate consumption of nutritional supplements among athletes. We conducted a structured research in PubMed database and through snow ball strategy. Search equation: 'Questionnaire' AND 'Supplementation' AND 'Athletes'. Inclusion criteria: published in any country in English or Spanish, containing questionnaire or indicators can be deducted from the items, to estimate the intake and use of nutritional supplements and should be targeted to athletes training in order to compete at any level. We performed a descriptive analysis. Results: 21 above the 122 identified studies met the inclusion criteria. Sociodemographic factors, sport and training frequency, athlete population, reasons/motives for use and consumption, sources of information and list of supplements and frequency are the found indicators for estimating intake of supplements. Discussion: there are great heterogeneity in terms of the proposed indicators by the authors at the question naires and intake estimation using nutritional supplements, standardization of the methodology for the development questionnaires to be necessary and proposing the classification of the Australian Institute of Sport as a reference (AU)

Composición corporal y somatotipo en triatletas universitarios / Body composition and somatotype in university triathletes

Introducción: el triatlón es un deporte de resistencia e individual que está formado por tres disciplinas diferentes: natación, ciclismo y carrera a pie. El objetivo del estudio es describir las características antropométricas en triatletas varones universitarios, además de analizar y describir la composición corporal y el somatotipo de dichos triatletas. Metodología: estudio observacional y descriptivo de las características antropométricas, la composición corporal y el somatotipo de 39 triatletas varones universitarios entre 24±4,5 años, participantes en el campeonato de España universitario de triatlón, modalidad sprint (Alicante 2010), procedentes de diferentes universidades españolas. Según la técnicas de medición antropométrica adoptadas por la International Society for the Advancement of Kinanthropometry (ISAK) y el Grupo Español de Cineantropometría (GREC) por un evaluador acreditado ISAK de nivel II. Resultados: nos encontramos con deportistas de talla baja, en los que destacan valores inferiores a lo normal en los pliegues cutáneos subescapular, supraespinal, tricipital y bicipital, un porcentaje de masa muscular (45,27±3,29%), de masa grasa (10,22±2,92%) y de masa ósea (16,65±1,34%) y un somatotipo en el que predomina la mesomorfia. Discusión: los triatletas y corredores presentan más baja talla que los ciclistas y nadadores. Los triatletas y ciclistas muestran un peso similar, siendo menor que el de los nadadores de fondo y mayor que el de los corredores de 10 km. Los pliegues cutáneos cresta ilíaca, abdominal y muslo frontal de los ciclistas son inferiores al de los triatletas. El porcentaje de masa grasa de triatletas corredores y nadadores son similares; sin embargo, el de la masa muscular de los triatletas suele ser inferior al de los ciclistas pero similar a las demás modalidades. El somatotipo del triatleta se asemeja al del ciclista (mesomorfo). El del corredor es mesomorfo-ectomorfo y el del nadador puede oscilar de mesomorfo a ectomorfo (AU)

Introduction: the triathlon is an endurance sport and individual that consists of three different disciplines: swimming, cycling and running. The aim of the study was to describe and analyze the anthropometric characteristics, body composition and somatotype in male college triathletes. Methodology: observational and descriptive study of anthropometric characteristics, body composition and somatotype of 39 male college athletes from 24±4,5 years, participants in the championship of Spain university triathlon sprint mode (Alicante 2010), from different universities Spanish. According to anthropometric measurement techniques adopted by the International Society for the Advancement of Kinanthropometry (ISAK) and the Spanish Group Cineantropometría (GREC) by an accredited assessor ISAK Level II. Results: we find athletes of stunting, where you destacanvalores below normal in the subscapularis, supraspinatus, triceps and biceps skinfold, percentage of muscle mass (45.27±3.29%) and fat mass (10.22±2.92%) and bone (16.65±1.34%) and where mesomorphy somatotipo predominates. Discussion: the triathletes and runners have lower size that cyclists and swimmers. Triathletes and cyclists show a similar weight, less than swimmers line, and more than 10km runners. Iliac crest skinfold, abdominal and thigh front cyclists are less than triathletes. The percentage of fat mass of runners triathletes and swimmers are similar, however the muscle mass of athletes usually less than cyclists but similar to other forms. Somatotype resembles triathlete cyclist (mesomorph). The corridor is ectomorph and mesomorph-swimmer can range from a ectomorph mesomorph (AU)

Efectos de los aminoácidos ramificados en deportes de larga duración: revisión bibliográfica / Effects of branched amino acids in endurance sports: a review

Introducción: El informe emitido por la Agencia Europea de Seguridad Alimentaria (EFSA) en 2010 sobre las declaraciones nutricionales y propiedades saludables, muestra que no existen evidencias científicas que apoyen la suplementación con aminoácidos ramificados (BCAAs). El objetivo de este estudio es analizar los efectos del consumo de suplementos de BCAAs en deportes de larga duración (DLD). Métodos: Estudio descriptivo de revisión bibliográfica sobre el estado actual del efecto del consumo de suplementos de BCAAs. Se realizó una búsqueda en la base de datos PubMed y estrategia de bola de nieve. Criterios de inclusión: Estudios realizados en humanos, ensayos clínicos controlados aleatorizados (ECCA) en castellano/inglés relacionados con el consumo de BCAAs, leucina, valina e isoleucina en DLD y sus efectos sobre el daño muscular, rendimiento deportivo, fatiga central, respuesta anabólica y sistema inmunológico publicados en cualquier país hasta mayo 2014. Resultados: De los 330 estudios identificados, 14 cumplieron los criterios de inclusión. La media de sujetos participantes en los estudio es igual a (11,36 ± 7,43). Sólo dos estudios incluyen un grupo de mujeres. Las disciplinas deportivas que se encontraron en los estudios fueron carrera a pie, ciclismo, combinación ciclismo y carrera a pie, triatlón distancia olímpica y un estudio que incluía 2 grupos de deportistas (triatlón distancia olímpica y carrera a pie). Se estudian los efectos de los BCAAs y daño muscular, rendimiento deportivo, fatiga central, respuesta anabólica en periodo de recuperación y respuesta inmunológica en periodos diferentes del entrenamiento: antes, durante y después o una combinación de éstos Discusión: Se observa que existe un menor grado de dolor y daño muscular, menor percepción del esfuerzo y fatiga mental, mayor respuesta anabólica en periodo de recuperación y mejora de la respuesta inmunológica cuando se suplementa con BCAAs, no obstante su toma antes o durante la actividad física no mejora el rendimiento deportivo. No se ha encontrado consenso en la dosis y cronología de la toma más eficaz, aunque es más efectivo si hay una relación 2-3/1/1g, entre los aminoácidos Leucina/ Isoleucina y Valina (AU)

Introduction: The report issued by the European Food Safety Agency (EFSA) in 2010 on nutrition and health claims, shows that there is no scientific evidence to support supplementation with branched chain amino acids (BCAAs). The aim of this study is to analyze the effects of consumption of BCAAs in endurance sports. Methods: A literature review on the current state of the effect of consumption of dietary supplements of BCAAs. We conducted a search in the PubMed database and snowball strategy. Inclusion criteria: Spanish / English randomized clinical trial related to the consumption of BCAAs, leucine, valine and isoleucine in endurance sports and its effects on muscle damage, athletic performance, central fatigue, anabolic signals during recovery and immune system response published in any country until May 2014. Results: Out of 330 studies identified, 14 met the inclusion criteria. The mean of subjects participating in the study was (11.36±7.43). Only two studies included a group of women. The sports that we found in the studies were: run, cycling, combining cycling and running, Olympic distance triathlon and one study included 2 groups of athletes (Olympic distance triathletes and runners). The effects of BCAAs and muscle damage, athletic performance, central fatigue, anabolic signals during recovery period and immune response were studied at different times: before, during and after training or a combination of these. Discussion: It is observed that there is a lesser degree of pain and muscle damage, less perceived exertion and mental fatigue, greater anabolic response in recovery period and improved immune response when supplemented with BCAAs, notwithstanding its decision before or during physical activity does not improve athletic performance. No consensus was found in the dose and timing of the most effective decision, although it is more effective if there is 2-3/1/1g relationship between leucine / isoleucine and valine amino acids (AU)

Report of the clinical donor case workshop of the European Association of Tissue Banks Annual Congress 2013.

The European Association of Tissue Banks (EATB) Donor Case Workshop is a forum held within the program of the EATB Annual Congress. The workshop offers an opportunity to discuss and evaluate approaches taken to challenging donor selection and donation ethics, and it strengthens networking between tissue banking professionals. The workshops actively engage participants from a wide array of international expertise, in an informal, secure and enjoyable setting in which learning from peers and finding potential solutions for submitted cases are facilitated. This report reflects some of the discussion at the Donor Case Workshop during the EATB Annual Congress in Brussels in 2013. The presented cases demonstrate that the findings, their interpretation, the resulting actions and preventive measures in the different tissue facilities are not always predictable. The varied responses from participants and lack of consensus corroborate this and clearly indicate that operating procedures do not comprehensively cover or prepare for all eventualities. For many of the issues raised there is no relevant information in the published literature. By publication of a summary of the discussions we hope to reach a wider audience, to provide information gathered at the workshop and to stimulate individuals and institutions to undertake further literature reviews or to undertake research in order to gather evidence concerning the discussed topics.

[Effects of branched amino acids in endurance sports: a review]. / Efectos de los aminoácidos ramificados en deportes de larga duración: revisión bibliográfica.

INTRODUCTION: The report issued by the European Food Safety Agency (EFSA) in 2010 on nutrition and health claims, shows that there is no scientific evidence to support supplementation with branched chain amino acids (BCAAs). The aim of this study is to analyze the effects of consumption of BCAAs in endurance sports. METHODS: A literature review on the current state of the effect of consumption of dietary supplements of BCAAs. We conducted a search in the PubMed database and snowball strategy. INCLUSION CRITERIA: Spanish / English randomized clinical trial related to the consumption of BCAAs, leucine, valine and isoleucine in endurance sports and its effects on muscle damage, athletic performance, central fatigue, anabolic signals during recovery and immune system response published in any country until May 2014. RESULTS: Out of 330 studies identified, 14 met the inclusion criteria. The mean of subjects participating in the study was (11.36±7.43). Only two studies included a group of women. The sports that we found in the studies were: run, cycling, combining cycling and running, Olympic distance triathlon and one study included 2 groups of athletes (Olympic distance triathletes and runners). The effects of BCAAs and muscle damage, athletic performance, central fatigue, anabolic signals during recovery period and immune response were studied at different times: before, during and after training or a combination of these. DISCUSSION: It is observed that there is a lesser degree of pain and muscle damage, less perceived exertion and mental fatigue, greater anabolic response in recovery period and improved immune response when supplemented with BCAAs, notwithstanding its decision before or during physical activity does not improve athletic performance. No consensus was found in the dose and timing of the most effective decision, although it is more effective if there is 2-3/1/1g relationship between leucine / isoleucine and valine amino acids.

Introducción: El informe emitido por la Agencia Europea de Seguridad Alimentaria (EFSA) en 2010 sobre las declaraciones nutricionales y propiedades saludables, muestra que no existen evidencias científicas que apoyen la suplementación con aminoácidos ramificados (BCAAs). El objetivo de este estudio es analizar los efectos del consumo de suplementos de BCAAs en deportes de larga duración (DLD). Métodos: Estudio descriptivo de revisión bibliográfica sobre el estado actual del efecto del consumo de suplementos de BCAAs. Se realizó una búsqueda en la base de datos PubMed y estrategia de bola de nieve. Criterios de inclusión: Estudios realizados en humanos, ensayos clínicos controlados aleatorizados (ECCA) en castellano/inglés relacionados con el consumo de BCAAs, leucina, valina e isoleucina en DLD y sus efectos sobre el daño muscular, rendimiento deportivo, fatiga central, respuesta anabólica y sistema inmunológico publicados en cualquier país hasta mayo 2014. Resultados: De los 330 estudios identificados, 14 cumplieron los criterios de inclusión. La media de sujetos participantes en los estudio es igual a (11,36 ± 7,43). Sólo dos estudios incluyen un grupo de mujeres. Las disciplinas deportivas que se encontraron en los estudios fueron carrera a pie, ciclismo, combinación ciclismo y carrera a pie, triatlón distancia olímpica y un estudio que incluía 2 grupos de deportistas (triatlón distancia olímpica y carrera a pie). Se estudian los efectos de los BCAAs y daño muscular, rendimiento deportivo, fatiga central, respuesta anabólica en periodo de recuperación y respuesta inmunológica en periodos diferentes del entrenamiento: antes, durante y después o una combinación de éstos. Discusión: Se observa que existe un menor grado de dolor y daño muscular, menor percepción del esfuerzo y fatiga mental, mayor respuesta anabólica en periodo de recuperación y mejora de la respuesta inmunológica cuando se suplementa con BCAAs, no obstante su toma antes o durante la actividad física no mejora el rendimiento deportivo. No se ha encontrado consenso en la dosis y cronología de la toma más eficaz, aunque es más efectivo si hay una relación 2-3/1/1g, entre los aminoácidos Leucina/ Isoleucina y Valina.

Tipo de bebidas consumidas por los estudiantes universitarios / Types of beverages consumed by university students

Fundamentos: Existe una gran diferencia entre el consumo de agua y las bebidas que contiene agua (bebidas carbonatadas, azucaradas, zumos o bebidas alcohólicas). El consumo de estas bebidas está relacionado con el desarrollo de enfermedades crónicas (obesidad, diabetes tipo 2, hipertensión arterial o dislipemias). El objetivo es determinar la frecuencia de consumo de bebidas de los estudiantes de la Universidad de Alicante. Métodos: Estudio transversal descriptivo. Población 26.273 estudiantes. Se seleccionaron 396 mediante muestreo aleatorio simple. Se utilizó un cuestionario frecuencia consumo para estimar la ingesta individual. Variables: bebidas (n=12) y frecuencia de consumo (n=4). Resultados: El 29,6% de hombres y el 13,0% de mujeres consumen bebidas carbonatadas con azúcar a diario (p-valor<0,001). El consumo diario de vino es nulo. El 41,4% de la población consume cerveza y destilados semanalmente. El 76,1% de hombres y el 58,7% de mujeres, consumen alcohol como mínimo una vez a la semana, p-valor=0,001. Conclusiones: Los resultados plantean la necesidad de estudios epidemiológicos que orienten el desarrollo de políticas nutricionales dirigidas a reducir el consumo de bebidas azucaradas y alcohólicas entre la población joven. Mediante un trabajo conjunto entre las autoridades gubernamentales, medios de comunicación, industria alimentaria y la sociedad en general (AU)

Background: There is a difference between drinking water and water-containing drinks (soft drinks, sugary juices or alcoholic beverages). The consumption of these beverages is related to the development of chronic diseases (obesity, type 2 diabetes, hypertension or dyslipidemia). The objective is to determine the frequency of consumption of different types of drinks of students at the University of Alicante. Methods: Descriptive cross-sectional study. From a population of 26,273 students, a sample of 396 was selected by simple random sampling. Frequency questionnaire was used to estimate beverage consumption, including as variables beverages (n = 12) and frequency of consumption (n = 4). Results: 29.6% of men and 13.0% of women consumed sugary soft drinks daily (p-value <0.001). Daily consumption of wine is null. The 41.4% of the population consumed beer and spirits weekly. 76.1% of men and 58.7% of women consumed alcohol at least once a week, p-value = 0.001. Conclusions: The results suggest the need for epidemiological studies to guide the development of nutrition policies aimed at reducing consumption of sugary drinks and alcohol among young people through a partnership between government authorities, media, food industry and society in general (AU)